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2009 Pilot Project Awards
The Colorado Clinical & Translational Sciences Institute (CCTSI) at the University of Colorado Denver is pleased to announce the awarding of 39 Pilot Project Awards to clinical and translational investigators of the University of Colorado, its CCTSI affiliated institutions and community partners. A total of $963,214 was awarded for 14 projects in the CO-Pilots Program (including 2 Team Science, 1 Mentored Pilot, 2 Independent Investigator, and 9 Junior Investigator), 9 projects in Child and Maternal Health Research, and 16 projects in Community Engagement and Research. These projects were chosen by rigorous scientific review from a total of 143 applications submitted for consideration. Below is a comprehensive listing of the successful Pilot Projects. Please join us in congratulating these talented investigators. |
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Pilot Type |
Primary Investigator |
Institutional Affiliate |
Co-Investigators |
Title of Project |
| Team Science Award |
Ivor S. Douglas MD, MRCP(UK) |
Denver Health, Medical Intensive Care |
Co-I: Connie Price, MD, Sub-Investigators/ Collaborators: Mark Moss, MD, Dave Howsen, PhD, Steve Metzger, PhD, Bob Wolken, RRT, Brian Day, PhD, Research Coordinators: Katie Overdier, MSc, Shelley Cooper, BSc |
Rapid bacterial identification and antibiotic resistance testing in critically ill adults at risk for ventilator acquired pneumonia (VAP) |
| Team Science Award |
Robert A. Sclafani, PhD |
UCD-SOM, Department of Biochemistry and Molecular Genetics |
Co-I's: Raj Agarwal, Ph.D., Pharmacy, Department of Pharmaceutical Sciences; David Raben, M.D., Medicine, Department of Radiation Oncology, Barbara Frederick, Ph.D., Medicine, Department of Radiation |
Oncology Combined Resveratrol and Radiation Therapy in Head and Neck Cancer |
| Mentored Pilot |
Kent Hansen, PhD |
UCD-SOM, Department of Medicine, Division of Geriatric Medicine |
Co-mentors: Wendy Kohrt, PhD; Rocio Pereira, MD |
Effects of Estrogen on Adipogenesis |
| Junior Investigator |
Irene Schauer, MD, PhD |
UCD-SOM, Department of Medicine, Division of Endocrine, Metabolism, and Diabetes |
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Postprandial lipemia and nocturnal fatty acids in type 1 diabetics compared to nondiabetic controls; a possible mechanism for increased CVD risk in type 1 diabetes |
| Junior Investigator |
Kristen Nadeau, MD |
UCD-SOM, Department of Pediatrics, Division of Pediatric Endocrinology |
Boris Draznin, MD,PhD, Phil Zeitler, MD, PhD, Mark Brown, PhD and Judith Regensteiner, PhD |
Muscle Metabolism in Youth with Type 1 and Type 2 Diabetes |
| Junior Investigator |
Kerrie L. Moreau, PhD |
UCD-SOM, Department of Medicine, Division of Geriatric Medicine |
Jane E. B. Reusch, MD |
The role of vascular inflammation in mediating arterial stiffening with sex hormone deficiency in healthy men |
| Junior Investigator |
Melissa Mahoney, PhD |
University of Colorado, Boulder Department of Chemical & Biological Engineering |
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Sustained Delivery of IL10 pDNA for the Treatment of Neuropathic Pain |
| Junior Investigator |
Leonard L. Dragone MD, PhD |
National Jewish Health, Pediatric Rheumatology |
Virginia D. Winn M.D., Ph.D |
Defining the mechanism of arthritis remission in pregnancy |
| Junior Investigator |
Hubert Yin, PhD |
University of Colorado,Boulder Department of Chemistry and Biochemistry |
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Optimizing the Clinical Efficacy of Opioids by TLR4 Blockade |
| Junior Investigator |
Lucy Golden, PhD |
UCD-SOM, Department of Medicine, Division of Gastroenterology & Hepatology |
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Engineering T Cells in Chronic HCV to Confer Novel Reactivity by Using HCV-Specific T Cell Receptor Gene Transfer |
| Junior Investigator |
Jena French, PhD |
UCD-SOM, Department of Medicine, Division of Endocrine, Metabolism, and Diabetes |
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Immune Suppression and Papillary Thyroid Cancer |
| Junior Investigator |
Michelle Barron, MD |
UCD-SOM, Department of Medicine, Division of Infectious Diseases |
Robert Knight, PhD, and Elizabeth Costello, PhD |
Identifying determinants of antibiotic-associated Clostridium difficile diarrhea |
| Independent Investigator |
Steven Moulton, MD |
UCD-SOM, Department of Pediatrics, Division of Pediatric Surgery |
Greg Grudic, PhD A |
Machine Learning Approach to the Non-Invasive Detection of Acute Blood Loss |
| Independent Investigator |
Yiping Du, PhD |
UCD-SOM, Department of Psychiatry |
Jody Tanabe, MD, James Kelly, MD |
Detection of Micro-hemorrhage in Traumatic Brain Injury Using Magnetic Resonance Imaging |
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Primary Investigator |
Institutional Affiliate |
Co-Investigators |
Title of Project |
| Neil Box, PhD |
School of Medicine, Dermatology |
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Gene and environmental influences on melanoma risk phenotypes in Colorado Children |
| Karim El Kasmi, MD, PhD |
School of Medicine, Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition |
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Role of innate immunity in the pathogenesis of parenteral nutrition associated liver injury in infants |
| Cindy Freehauf, RN, MS, CGC |
School of Medicine, Pediatrics |
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The Oxidative stress and inflammation makers in homocysteimia due to cystathionine beta-synthase deficiency: investigation of their presence and contribution to the natural history of the disease across the life span of affected individuals and the impact of taurine on these markers |
Karen Jonscher, PhD
Virginia Ferguson PhD |
School of Medicine, Anesthesiology
College of Engineering, Mechanical Engineering |
James McManaman, PhD, School of Medicine, Physiology & Biophysics
Ron Gibbs, MD, School of Medicine, Obstetrics & Gynocology |
Correlating Biomechanical and Biochemical Mechanisms to Predict Preterm Premature Rupture of Membranes (PPROM) in Pregnancy |
| Jenn Leiferman, PhD |
School of Public Health, Epidemiology Dept |
Betsy Corwin, PhD, School of Nursing, Nursing
Mary Coussons-Read, PhD, School of Medicine, Psychology |
The effect of an antenatal physical activity pilot intervention on maternal stress, biomarkers, and preterm delivery |
Ellyn Matthews, PhD
Madalynn Neu, PhD, RN
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College of Nursing, Nursing
College of Nursing, Nursing |
Tim Garrington, MD, School of Medicine, Pediatrics Center for Cancer/Blood Disorders
Paul Cook, PhD, College of Nursing, Center for Nursing Research
Nancy King, RN, MSN, CPNP, Children’s Hospital Pediatrics, Center for Cancer/Blood Disorders |
Caregiver-Child Sleep Patterns and Distress During Maintenance Therapy for Acute Lymphocytic Leukemia |
| Yogendra Raol, PhD |
School of Medicine, Pediatrics |
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Potassium channel opener for the prevention of seizures and neuronal injury following neonatal hypoxia-ischemia |
| Nancy West, PhD |
School of Public Health, Epidemiology |
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The Environmental Factors in Early Life, DNA Methylation, and Fetal Origins of Diseases Across the Lifespan |
| Samantha Woodruff, MD |
TCH, Pediatric Gastroenterology |
Sophie Fillon PhD, School of Medicine, Pediatric Gastroenterology
Mark Lovell, MD, School of Medicine, Pediatric Pathology
Rubin Tuder, School of Medicine, Pulmonary Pathology
Dan Atkins, MD, National Jewish Hosopital, Pediatric Allergy
Steve Freeman, MD, School of Medicine, Adult Gastroenterology |
Mechanisms of Esophageal Fibrosis |
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Community Partner |
Primary Investigator |
Institutional Affiliate |
Co-Investigators |
Title of Project |
| McKinley Community Health Alliance, MCHA - Gallup, NM |
Teresa Sharp, PhD |
University of Colorado Denver, School of Medicine, Department of Pediatrics Section of Nutrition |
Academic: Elizabeth Gilbert, EdD, University of Northern Colorado, School of Public Health, Community Health Education; Sharon Shields, PhD, Vanderbilt University; Laurel Lunn, Vanderbilt University
Community: Ina Burmeister, BA, MA, Rehoboth McKinley Christian Health Care Services |
A Mixed-Methods Community Based Participatory Research Study to Expand Intercultural Understanding of the Long-Term Detrimental Effects of Childhood Obesity |
| Denver Department of Human Services |
Heather Taussig, PhD |
University of Colorado Denver, School of Medicine, Department of Pediatrics Kempe Childrens Center |
Community: Melissa Carson |
Collaborative Development of a Protocol to Assess Health Disparities Among Maltreated Youth with a History of Foster Care Placement |
| Elkhart Community |
Allegra Melillo, MD |
University of Colorado Hospital, University Family Medicine |
Academic: Mark Earnest, MD, University of Colorado Hospital, University Medicine; Amy Barton, RN, PhD, University of Colorado Denver, School of Nursing
Community: Marybeth Rensberger, RN, Aurora Public School District; Katie Hartenbach, Elkhart Elementary School |
Developing a Community-Based Participatory Research Infrastructure to Support the Development of an Interprofessional Student-Run School-Based Health Center |
| Denver Urban Gardens |
Jill Litt, PhD |
University of Colorado Boulder, Colorado School of Public Health, Department of Environmental & Occupational Health |
Community: Michael Buchenau, MLA, GGHC; Laura Lavid, GGHC; Joe Brown, Starz Down to Earth Films |
Gardens for Growing Healthy Communities (GGHC) |
| Project PAVE, East High School |
Eric Sigel, MD |
University of Colorado Denver, School of Medicine, Department of Pediatrics Section of Adolescent Medicine |
Community: Adam Evans/Mike Johnson - Project PAVE; John Youngquist, Principal East High School |
Screening and Treating Youth at Risk for Violence Involvement in the School Setting |
| Community Data Review and Dissemination Group - 2040 |
Patricia Iwasaki, MSW |
University of Colorado Denver, Department of Family Medicine, Department of Health and Behavioral Sciences |
Academic: Debbi Main, PhD, University of Colorado Denver
Community: Tracey Stewart; George Ware |
Using Social Networks and Small Groups to Explore Interpretations of Taking Neighborhood Health to Heart (TNH2H) Data and Collect Outlier Pilot Data |
| Spring Institute for Intercultural Learning; Refugee Preventive Health Services Program of Colorado; Colorado Progressive Coalition; Colorado African Organization; Denver Health |
Jini Puma, PhD |
University of Colorado Denver, Colorado School of Public Health, Rocky Mountain Prevention Research Center |
Academic: Dr. Martin Tombari, University of Denver, Colorado Community-Based Research Network (CCBRN); Dr. Laurie Bennett, University of Denver, CCBRN; Dr. Nicholas Cutforth, University of Denver, CCBRN; Dr. Janet Shriberg, University of Denver, International Disaster Psychology Program
Community: Susan Downs-Karkos - Spring Institute; Barbara Hummel/Matthew Kelly - Refugee Preventive Health Services Program of Colorado; Paul Stein - Colorado Refugee Services Program; Francoise Mbabazi - Colorado Progressive Coalition; Dr. Khalid Mohammed - Colorado African Organization; Dr. Gretchen Heinrichs - Denver Health |
What Gets Lost in the Translation? Why Refugees with Abnormal Health Conditions Fail to Seek Follow-up Medical Care |
| Montbello and Green Valley Ranch - New Beginnings Nursing Assistant Program |
Chris Bryant, RN (Community PI) |
Montbello/Green Valley Ranch Leadership Coalition (MGVRLC) and Colorado Council of Black Nurses (CCBN) |
Academic partnership to be determined
Community: Tracy Williams, TradeWinds Communications, LLC; Dr. Margie Cook, Colorado Council of Black Nurses; Leslie Sterling, LCSW, Mental Health Center of Denver; Sia Chandler-Garcia, Denver Public Schools; Kelly O'Keefe Voorhees, MSPH, Colorado Department of Public Health and Environment |
Community/Academic Partnership to Increase Certified Nursing Assistant (CNA) Graduates in Minority Residents in the Montbello and Green Valley Ranch Community |
| Community Research, Education, Awareness (CREA) |
Arnold Levinson, PhD |
University of Colorado Denver, Colorado School of Public Health, Department of Community & Behavioral Health |
Community: Fernando Pineda-Reyes |
Community-Embedded Navigators and Health Promotores for Disease Prevention and Treatment |
| To be determined |
Karen Peifer, PhD |
University of Colorado Denver, College of Nursing |
Academic: Mary Weber, PhD, APRN, PMHNP-BC, University of Colorado Denver, College of Nursing, Psychiatric Nurse Practitioner Program |
Design and Development of a Community Needs Assessment Tool Based on Standardized Measures: Focus on Unmet Needs Related to Maternal Depression |
| Metro Denver Hospice |
Jean Kutner, MD, MSPH |
University of Colorado Denver, School of Medicine Department of Medicine, Division of General Internal Medicine |
Community: Janelle McCallum, RN, MSM, CHPN, BSN; Susan Lasker-Hertz, RN, MSN, CHPN |
Hospice-Academic Partnership to Improve Care for Vulnerable Populations at the End of Life |
| Salud Family Health Centers/CaReNet (SNOCAP) |
Jennifer Morse (Community PI) |
Salud Family Health Centers |
Academic: Bennett Parnes, MD, University of Colorado Denver, School of Medicine, Department of Family Medicine, Division of Geriatrics
Community: Tillman Farley, MD |
Identify the Health Care Needs of a Geriatric Hispanic Population Affected by Range of Health Disparities |
| N.O.V.A. (Nurturing Our Village Association) |
Bridgette Larkin (Community PI) |
Founder, N.O.V.A. |
Academic partnership to be determined
Community: Margie Cook, PhD, NP, RN, Colorado Council of Black Nurses |
Nurturing Our Village Association |
| High Plains Research Network |
Linda Zittleman, MSPH |
University of Colorado Denver, School of Medicine, Department of Family Medicine |
Academic: Bennett Parnes, MD, University of Colorado Denver, Department of Family Medicine; Lauren DeAlleaume, MD, Denver Health; Elaine Belansky, PhD, University of Colorado Denver, Colorado School of Public Health; Jack Westfall, MD, University of Colorado Denver, Department of Family Medicine
Community: Shirley Cowart - Yuma; Maret Felzien - Sterling; Mike Hernandez - Ovid; Emily Mollohan - Sterling; Ned Norman - Sterling; Mary Rodriquez - Fort Morgan; Norah Sanchez - Yuma; Sergio Sanchez - Yuma; Carly Schrade - Sterling; Kathy Winkelman - Limon; Steve Winkleman - Limon |
Partnering to Improve Health on the Eastern Plains |
| Aurora Mental Health Center |
Evelin Gomez, PhD |
University of Colorado Denver, School of Medicine, Department of Pediatrics, Kempe Childrens Center |
Community: Betsy Rogers, LCSW |
Providing Evidence-Based Treatments to Enhance the Mental Health of Latino Children and Families |
| San Luis Valley |
Nick Cutforth, PhD |
University of Denver, Colorado Community-Based Research Network |
Elaine Belansky, PhD, University of Colorado Denver, Colorado School of Public Health, Rocky Mountain Prevention Research Center; Robert Chavez, Rocky Mountain Prevention Research Center John Naranjo, San Luis Valley schools; Tony Laker/Margie Miller, Adams State College |
The San Luis Valley Physical Education Collaborative |
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